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Sources

Every claim on this site traces to a source below: published studies and official guidance. Both change, so check each source for its latest date. We last reviewed these sources on October 26, 2026.

PublisherSourceWhat we used it for
Peer-reviewed studyBergamaschi et al., Neuropsychopharmacology, 2011 (randomized, double-blind)Randomized trial, 24 people with social anxiety; CBD reduced anxiety in a speaking test.
Peer-reviewed studyCoelho et al., Life, 2024 (systematic review of 15 randomized trials)Systematic review of 15 randomized trials of CBD for anxiety; mixed results.
Peer-reviewed studyGournay et al., Psychopharmacology, 2023 (randomized, placebo-controlled)Randomized trial, 63 people; repeated 300 mg reduced anxiety symptoms but not worry.
Peer-reviewed studyShannon et al., The Permanente Journal, 2019 (retrospective case series)Chart review of 72 adults for anxiety and sleep; no placebo group.
Peer-reviewed studyElms et al., Journal of Alternative and Complementary Medicine, 2019 (case series)Case series of 11 adults with PTSD; no placebo group.
Peer-reviewed studyBolsoni et al., Psychopharmacology, 2022 (randomized, double-blind)Randomized trial, 33 people with PTSD; 300 mg CBD before trauma recall.
Peer-reviewed studyNarayan et al., Journal of Clinical Sleep Medicine, 2024 (randomized pilot)Randomized pilot, 30 adults with insomnia; mostly no difference from placebo.
Peer-reviewed reviewMoore et al., The Journal of Pain, 2024 (review of CBD pain trials)16 randomized trials of CBD for pain; 15 showed no benefit over placebo.
Trade publication (secondary)NeurologyLive: FDA approves cannabidiol for Lennox-Gastaut and Dravet syndromesEpidiolex approval and Lennox-Gastaut trial results.
VA/DoDVA/DoD PTSD Clinical Practice Guideline, Quick Reference (v4.0, 2023)Recommendation 20 is a strong recommendation against cannabis or cannabis-derived products for PTSD.
VA National Center for PTSDVA National Center for PTSD: Cannabis Use and PTSD Among Veterans (updated Sept. 3, 2025)Evidence, risks and use rates among veterans.
VA Public HealthVA Public Health: VA and Marijuana, What Veterans Need to Know (updated Aug. 1, 2023)Benefits, provider roles, prescribing and VA grounds.
Battle Creek VA clinicians (peer-reviewed)Petersen et al., Effect of cannabis use on PTSD treatment outcomes in veterans, The Mental Health Clinician, 2021Chart review of 340 veterans in a PTSD program. Did not study CBD separately.
NIH (NCCIH)NIH NCCIH: Cannabis (Marijuana) and Cannabinoids: What You Need To Know (2019)Evidence on pain, anxiety, PTSD and sleep; FDA-approved cannabinoid drugs; safety.
NIH (NCCIH)NIH NCCIH news release on cannabinoid pain research (Sept. 19, 2019)Pain research support described as weak; nine new research grants.
FDAFDA: What You Need to Know (and What We're Working to Find Out) About Products Containing Cannabis or Cannabis-Derived Compounds, Including CBDOne approved CBD drug; unapproved products; side effects; liver injury; interactions; label accuracy.
FTCFTC: Serious health claims for CBD products need proofHealth claims for CBD need competent and reliable scientific evidence.
Veterans Crisis LineVeterans Crisis LineDial 988 then press 1; text 838255; online chat.
Foley Hoag (law firm, not a government source)Foley Hoag: A temporary reprieve for hemp-THC products (Sept. 2026)Federal hemp THC limit delayed to December 11, 2026.

How we write

  • We summarize in our own words and link to the original.
  • We report evidence that is limited or against, not just evidence that is favorable, and we give each study's size and design.
  • We label non-government sources.
  • We don't make claims that a product treats, cures or prevents any condition.

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